Multimeric ion channel
├──Trimeric ion channel ...
│  └──ATP-gated ion channel
├──Pentameric ion channel ...
│  └──Cys-loop ligand-gated ion channel ...
│     ├──Cationic cys-loop ligand-gated ion channel ...
│     │  ├──Acetylcholine-gated channel (nicotinic)
│     │  └──Serotonin-gated channel (5-HT3)
│     └──Anionic cys-loop ligand-gated ion channel ...
│        ├──GluCl glutamate-gated chloride channel
│        ├──Glycine-gated chloride channel
│        ├──Histamine-gated chloride channel
│        ├──Serotonin-gated anionic channel
│        └──GABA-gated anionic channel ...
│           ├──GABA C-gated anionic channel
│           └──GABA A-gated anionic channel ...
│              ├──GABRA1
│              └──GABRA2
├──Dimeric ion channel ...
│  └──Inwardly rectifying potassium channel ...
│     ├──Inwardly rectifying potassium channel - type 1 ...
│     │  └──Kir1.1
│     ├──Inwardly rectifying potassium channel - type 5 ...
│     │  └──Kir5.1
│     ├──Inwardly rectifying potassium channel - type 7 ...
│     │  └──Kir7.1
│     ├──Inwardly rectifying potassium channel - type 4 ...
│     │  ├──Kir4.1
│     │  └──Kir4.2
│     ├──Inwardly rectifying potassium channel - type 6 ...
│     │  ├──Kir6.1
│     │  └──Kir6.2
│     ├──Inwardly rectifying potassium channel - type 2 ...
│     │  ├──Kir2.1
│     │  ├──Kir2.2
│     │  ├──Kir2.3
│     │  └──Kir2.4
│     └──Inwardly rectifying potassium channel - type 3 ...
│        ├──Kir3.1
│        ├──Kir3.2
│        ├──Kir3.3
│        └──Kir3.4
├──Tetrameric ion channel ...
│  ├──Glutamate-gated cationic channel ...
│  │  ├──AMPA-type glutamate-gated cationic channel
│  │  ├──Kainate glutamate-gated cationic channel
│  │  └──NMDA-type glutamate-gated cationic channel
│  ├──Cyclic-nucleotide gated channel ...
│  │  ├──Cyclic-nucleotide gated channel - type B ...
│  │  │  ├──CNGB1
│  │  │  └──CNGB3
│  │  └──Cyclic-nucleotide gated channel - type A ...
│  │     ├──CNGA1
│  │     ├──CNGA2
│  │     ├──CNGA3
│  │     └──CNGA4
│  └──Calcium-activated potassium channel ...
│     ├──Calcium-activated potassium channel - type 1 ...
│     │  └──Kca1.1
│     ├──Calcium-activated potassium channel - type 3 ...
│     │  └──Kca3.1
│     ├──Calcium-activated potassium channel - type 5 ...
│     │  └──Kca5.1
│     ├──Calcium-activated potassium channel - type 4 ...
│     │  ├──Kca4.1
│     │  └──Kca4.2
│     └──Calcium-activated potassium channel - type 2 ...
│        ├──Kca2.1
│        ├──Kca2.2
│        └──Kca2.3
├──Dimeric dimer ion channel ...
│  └──Two pore potassium channel ...
│     ├──Two pore potassium channel - type 1 ...
│     │  └──K2p1.1
│     ├──Two pore potassium channel - type 2 ...
│     │  └──K2p2.1
│     ├──Two pore potassium channel - type 3 ...
│     │  └──K2p3.1
│     ├──Two pore potassium channel - type 4 ...
│     │  └──K2p4.1
│     ├──Two pore potassium channel - type 5 ...
│     │  └──K2p5.1
│     ├──Two pore potassium channel - type 6 ...
│     │  └──K2p6.1
│     ├──Two pore potassium channel - type 7 ...
│     │  └──K2p7.1
│     ├──Two pore potassium channel - type 9 ...
│     │  └──K2p9.1
│     ├──Two pore potassium channel - type 10 ...
│     │  └──K2p10.1
│     ├──Two pore potassium channel - type 12 ...
│     │  └──K2p12.1
│     ├──Two pore potassium channel - type 13 ...
│     │  └──K2p13.1
│     ├──Two pore potassium channel - type 15 ...
│     │  └──K2p15.1
│     ├──Two pore potassium channel - type 16 ...
│     │  └──K2p16.1
│     ├──Two pore potassium channel - type 17 ...
│     │  └──K2birnlex_annot.1
│     └──Two pore potassium channel - type 18 ...
│        └──K2p18.1
└──Multimeric Voltage-gated ion channel ...
   └──Tetrameric Voltage-gated ion channel ...
      ├──Hyperpolarization and cyclic-nucleotide gated channel ...
      │  ├──HCN1
      │  ├──HCN2
      │  ├──HCN3
      │  └──HCN4
      ├──Transient receptor potential related channel ...
      │  ├──Transient receptor potential related channel - two-pore type ...
      │  │  ├──TPC1
      │  │  └──TPC2
      │  ├──Transient receptor potential related channel - mucolipin type ...
      │  │  ├──TRPML1
      │  │  ├──TRPML2
      │  │  └──TRPML3
      │  ├──Transient receptor potential related channel - PKD type ...
      │  │  ├──TRPP1
      │  │  ├──TRPP2
      │  │  └──TRPP3
      │  └──Transient receptor potential related channel - sperm-specific Ca+2-selective type ...
      │     ├──CatSper1
      │     ├──CatSper2
      │     ├──CatSper3
      │     └──CatSper4
      ├──Transient receptor potential channel ...
      │  ├──ANKTM1
      │  ├──Transient receptor potential channel - type V ...
      │  │  ├──TRPV1
      │  │  ├──TRPV2
      │  │  ├──TRPV3
      │  │  ├──TRPV4
      │  │  ├──TRPV5
      │  │  └──TRPV6
      │  ├──Transient receptor potential channel - type C ...
      │  │  ├──TRPC1
      │  │  ├──TRPC2
      │  │  ├──TRPC3
      │  │  ├──TRPC4
      │  │  ├──TRPC5
      │  │  ├──TRPC6
      │  │  └──TRPC7
      │  └──Transient receptor potential channel - type M ...
      │     ├──TRPM1
      │     ├──TRPM2
      │     ├──TRPM3
      │     ├──TRPM4
      │     ├──TRPM5
      │     ├──TRPM6
      │     ├──TRPM7
      │     └──TRPM8
      └──Voltage-gated potassium channel ...
         ├──Voltage-gated potassium channel - type 5 ...
         │  └──Kv5.1
         ├──Voltage-gated potassium channel - type 2 ...
         │  ├──Kv2.1
         │  └──Kv2.2
         ├──Voltage-gated potassium channel - type 8 ...
         │  ├──Kv8.1
         │  └──Kv8.2
         ├──Voltage-gated potassium channel - type 10 ...
         │  ├──Kv10.1
         │  └──Kv10.2
         ├──Voltage-gated potassium channel - type 4 ...
         │  ├──Kv4.1
         │  ├──Kv4.2
         │  └──Kv4.3
         ├──Voltage-gated potassium channel - type 9 ...
         │  ├──Kv9.1
         │  ├──Kv9.2
         │  └──Kv9.3
         ├──Voltage-gated potassium channel - type 11 ...
         │  ├──Kv11.1
         │  ├──Kv11.2
         │  └──Kv11.3
         ├──Voltage-gated potassium channel - type 12 ...
         │  ├──Kv12.1
         │  ├──Kv12.2
         │  └──Kv12.3
         ├──Voltage-gated potassium channel - type 3 ...
         │  ├──Kv3.1
         │  ├──Kv3.2
         │  ├──Kv3.3
         │  └──Kv3.4
         ├──Voltage-gated potassium channel - type 6 ...
         │  ├──Kv6.1
         │  ├──Kv6.2
         │  ├──Kv6.3
         │  └──Kv6.4
         ├──Voltage-gated potassium channel - type 7 ...
         │  ├──Kv7.1
         │  ├──Kv7.2
         │  ├──Kv7.3
         │  ├──Kv7.4
         │  └──Kv7.5
         └──Voltage-gated potassium channel - type 1 ...
            ├──Kv1.1
            ├──Kv1.2
            ├──Kv1.3
            ├──Kv1.4
            ├──Kv1.5
            ├──Kv1.6
            ├──Kv1.7
            └──Kv1.8